Research & Patient Center

Clinical Trials and Studies

The Lois Insolia ALS Clinic at the Les Turner ALS Research and Patient Center at Northwestern University Medicine is actively involved in multi-center drug trials. Robert Sufit, MD, Senda Ajroud-Driss, MD and Pat Casey, MS, OTR/L, CCRC, oversee the various ALS therapeutic clinical drug trials.

For a listing of current drug trials being conducted at the clinic, please visit the clinical trials section of  the Centers for Disease Control website. General questions about eligibility for specific drug trials can be directed to

Information on ALS clinical trials being done at other locations nationwide can be found at the Northeast Amyotrophic Lateral Sclerosis Consortium (NEALS) website. 

Center Chosen as Only Site in Illinois for Phase 3 Clinical Drug Trial

The Foundation is pleased to announce the start of a new clinical drug trial for ALS at the Lois Insolia ALS Clinic at the Center.  VITALITY-ALS is a Phase 3 clinical trial designed to evaluate the safety and effectiveness of tirasemtiv, an investigatory drug candidate under evaluation for the potential treatment of ALS. The objective of the clinical trial is to assess the effect of tirasemtiv versus placebo on respiratory function.

The study is sponsored by Cytokinetics, a biopharmaceutical company in San Francisco, California.

People with ALS in Illinois who wish to be considered for this trial should email the Lois Insolia ALS Clinic.

More information about VITALITY-ALS can be found here.

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Meet our world-class ALS researchers:

Dr. Teepu Siddique

Dr. Teepu Siddique

The Les Turner ALS Research Laboratory led by Teepu Siddique, MD, focuses on understanding the processes by which ALS progresses so that effective treatments can be developed. The lab was first dedicated in 1979 and has been directed by Dr. Siddique since 1991.

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Dr. P. Hande Ozdinler

Dr. Hande Ozdinler

This lab, opened in 2008, focuses on the motor neurons which reside in the brain and connect with motor neurons in the spinal cord to initiate and control movement. These two motor neuron populations progressively degenerate in ALS patients, and therefore require immediate attention.

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Dr. Evangelos Kiskinis

Dr. Evangelos Kiskinis

The Les Turner ALS Foundation Research Laboratory led by Dr. Evangelos Kiskinis opened in January 2015. Dr. Kiskinis works on understanding the level and nature of heterogeneity in ALS and to identify points of effective and targeted therapeutic intervention.

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