Funding that ALS researchers at the Les Turner ALS Research and Patient Center receive has a huge impact on their discoveries. Joint funding from the Foundation along with other ALS sources has become crucial as researchers make translational progress toward …
Research Updates from Dr. Kiskinis’ Lab – September 2015
While the majority of ALS is sporadic, a relatively small, but highly informative, percentage of patients are diagnosed with mutations in various genes which include: SOD1, TDP43 and C9orf72. The goal of the Kiskinis lab is to characterize how these …
Research Updates from Dr. Siddique’s Lab – September 2015
Dr. Siddique will be giving an Internal Medicine Grand Rounds at Baylor Medical in September. entitled “Amyotrophic Lateral Sclerosis: Advances in the Understanding of Neurodegeneration.” This talk will help attendees understand what ALS is, how genetics contributes to the development of …
Research Updates from Dr. Kiskinis’ Lab – June 2015
The Evangelos Kiskinis Lab of Stem Cells and Neurodegeneration has now moved to its permanent location on the 12th floor of the Ward Building at the Feinberg School of Medicine. The lab is equipped with a dedicated cell culture room …
Research Updates from Dr. Ozdinler’s Lab – June 2015
The Ozdinler Lab generated a novel reporter line in which both the sensory and the motor neurons are genetically labeled with a fluorescent green protein, allowing visualization and precise cellular analyses for motor and sensory systems simultaneously. The lab previously …
Research Updates from Dr. Siddique’s Lab – June 2015
Sporadic amyotrophic lateral sclerosis (SALS) accounts for 90% of all cases of ALS. Its etiology is largely unknown and it is not well studied in African Americans. SALS is thought to be a complex disorder in which an individual inherits …
MMWR in Brief
The Center for Disease Control and Prevention’s MMWR in Brief summarizes key points from “Prevalence of Amyotrophic Lateral Sclerosis – United States, 2010-2011.” New information in this report includes the first prevalence estimate and description of demographic characteristics of ALS …
Registry Adds Two New Surveys
The Agency for Toxic Substances and Disease Registry (ATSDR) added two additional risk factor surveys to the National ALS Registry. The new surveys ask about head trauma and health insurance coverage. There are now a total of 17 surveys designed …
EMBO Journal – April 29, 2015
Last month the lab published a review on the potential of using stem cells to probe disorders of the central nervous system at the EMBO Journal. You can read the full manuscript here (http://emboj.embopress.org/content/34/11/1456.long) Evangelos and lab members also attended …
Research Updates from Dr. Siddique’s Lab – April 2015
In a recent study published by Cirulli et al (Science, 2015 Feb 19) whole exome sequencing of 2,874 ALS patients confirmed several known ALS genes and identified TBK1 as a novel ALS gene. TBK1 is known to be one of several …