A study from the Les Turner ALS Center at Northwestern Medicine has shed light on a critical molecular mechanism underlying amyotrophic lateral sclerosis (ALS), according to findings published in the journal Neuron. The research points to a failure in the …
A new clue to ALS and FTD: Faulty protein disrupts brain’s ‘brake’ system
Findings point to promising drug that restores neuron balance and may slow disease progression A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in …
Les Turner ALS Foundation to Make $500,000 Gift to Northwestern Research
Funding ensures promising new ALS therapies and vital research can continue In response to the current federal funding crisis, the Les Turner ALS Foundation is announcing that it will make a $500,000 gift to support ALS research at Northwestern University …
ALS drug effectively treats Alzheimer’s disease in new animal study
Experimental drug NU-9 — a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) — improves neuron health in animal models of Alzheimer’s disease, according to …
UPDATED: Statement on Proposed Cut to Congressionally Directed Medical Research Program for FY2025
Updated: On March 14, 2025, the Senate passed a bill that will fund the government through Sept. 30, 2025. We will continue to provide updates as we learn more about how these budget cuts will affect ALS research. This is …
LETTER: Neuromuscular Advocacy Groups Oppose NIH Indirect Cost Cap of 15%
On behalf of the approximately 300,000 Americans living with a neuromuscular disease (NMD), the undersigned 40 patient advocacy organizations strongly urge the National Institutes of Health (NIH) to immediately reverse and retract “Supplemental Guidance to the 2024 NIH Grants Policy …
URGENT: Tell Congress to Oppose Catastrophic Research Cuts
The National Institutes of Health (NIH) recently announced a major reduction in grant funding that would have a catastrophic impact on research, especially for neuromuscular diseases like ALS. NIH funding has led to amazing discoveries, including the underlying mechanisms of …
Introducing the New Participating in Clinical Research Tool
Deciding whether to participate in clinical research is a pivotal step for people living with ALS and their families. It’s a process often filled with important questions about risks, benefits, and expectations. Clear and reliable information is essential to empower …
National Institute on Aging invests an additional $7.3 million into NU-9
With its ability to improve neuron health, experimental drug NU-9 has already shown promise in reversing amyotrophic lateral sclerosis (ALS). Now, the National Institute on Aging (NIA) has provided approximately $7.3 million to fund exploration into the Northwestern University-invented drug’s …
Les Turner ALS Center at Northwestern Medicine and Sean M. Healey & AMG Center for ALS Establish Acceleration Centers of Enrollment Initiative
Together with the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital, the Les Turner ALS Center at Northwestern Medicine is thrilled to announce the launch of the Acceleration Centers of Enrollment (ACE) initiative. The ACE initiative …








