With its ability to improve neuron health, experimental drug NU-9 has already shown promise in reversing amyotrophic lateral sclerosis (ALS). Now, the National Institute on Aging (NIA) has provided approximately $7.3 million to fund exploration into the Northwestern University-invented drug’s …
Les Turner ALS Center at Northwestern Medicine and Sean M. Healey & AMG Center for ALS Establish Acceleration Centers of Enrollment Initiative
Together with the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital, the Les Turner ALS Center at Northwestern Medicine is thrilled to announce the launch of the Acceleration Centers of Enrollment (ACE) initiative. The ACE initiative …
New ALS research grants awarded for 2024
We’re excited to share the latest ALS research grants from the Les Turner ALS Center at Northwestern Medicine and highlight a new milestone: in 2024, the Les Turner ALS Foundation is funding more than $1 million in ALS research grants …
Making Clinical Research Accessible: Insights from a Research Professional
Clinical research at the Lois Insolia Clinic at the Les Turner ALS Center at Northwestern Medicine plays a pivotal role in helping researchers understand the causes of ALS and how to develop better treatments for the disease. But many people …
To find the cause of ALS, researchers look to metabolism within motor neurons
As researchers at the Les Turner ALS Center at Northwestern Medicine search for the root causes of ALS, they are examining processes within the body — even down to the cellular level. In fact, recent research has shown that people …
Harnessing the power of stem cells to find the drivers behind sporadic ALS
To better understand the molecular mechanisms that underlie ALS, researchers at the Les Turner ALS Center at Northwestern Medicine are harnessing the power of one of the 21st century’s most powerful medical tools: stem cells. In the lab of Evangelos …
How ALS is linked to the body’s circadian rhythms
Many people living with ALS find that their sleep is disrupted. But that disruption of their body’s 24-hour circadian rhythms might not just be a symptom of the disease. Researchers have found that this disrupted sleep actually contributes to the …
Understanding the connection between the immune system and ALS
Using cutting-edge techniques, researchers at the Les Turner ALS Center at Northwestern Medicine are working to test an innovative hypothesis: that the immune system is involved in the breakdown of the connection between the brain and muscles in people with …
Studies identify novel underpinnings of genetic ALS
A pair of recent studies from the laboratory of Evangelos Kiskinis, PhD, associate professor in the Ken and Ruth Davee Department of Neurology’s Division of Neuromuscular Disease and of Neuroscience and a member of the Les Turner ALS Center at Northwestern Medicine, have uncovered novel …
‘New’ ALS gene destabilizes neuron’s structure and chokes off its nucleus
As many as 2% of all ALS cases have been linked to mutations in the gene NEK1, making it one of the top-known causes of the disease. But it wasn’t known how the mutated gene disrupts the function of the …