We are excited to share some promising data regarding the CENTAUR trial evaluating AMX0035 in people with ALS on overall survival analysis, published today (October 16, 2020) in the neuromuscular disease journal Muscle & Nerve. The survival analysis followed each …
Data from Amylyx’s CENTAUR trial shows promise in slowing ALS progression
We are very pleased to share promising data published this week in the New England Journal of Medicine from the recent CENTAUR trial, conducted by Amylyx Pharmaceuticals, showing that AMX0035, the combination drug of sodium phenylbutyrate–taurursodiol, can slow functional decline …
Introducing the Joan & Paul Rubschlager Professorship
When Paul Rubschlager’s father was diagnosed with ALS in 1974, little was known about the cause of ALS and even less existed to help families facing this heartbreaking disease. After Paul’s father passed away in 1975, he and his wife …
Mechanisms Discovered Behind C9orf72 ALS Mutation
Evangelos Kiskinis, PhD, of our Les Turner ALS Center at Northwestern Medicine, alongside fellow Northwestern Medicine scientists, recently discovered the mechanisms and consequences behind ALS defect gene C9orf72. “A DNA mutation in a gene known as C9orf72 is responsible for …
New Study Evaluates Impact of Traumatic Brain Injury on ALS
The mission of our Les Turner ALS Center at Northwestern Medicine is to strive for a future without ALS by accelerating leading-edge research while providing life-enhancing treatment to people living with ALS. Our team at the Center, made up of …
Introducing the First-Ever ALS Platform Trial
The Sean M. Healey & AMG Center at Massachusetts General Hospital is launching the first-ever ALS platform trial aimed at advancing the development of ALS treatments. Our Lois Insolia ALS Clinic at the Les Turner ALS Center at Northwestern Medicine …
$3.1 Million NIA Grant for ALS Drug Therapies
Hande Ozdinler, PhD, Associate Professor of Neurology at Northwestern University Feinberg School of Medicine and a faculty member at our Les Turner ALS Center at Northwestern Medicine, was awarded a $3.1 million grant, over five years, from the National Institute …
Revised Airlie House ALS Clinical Trial Guidelines
In March 2016, Senda Ajroud-Driss, MD, Director of the Lois Insolia ALS Clinic, Associate Professor of Neurology and Teepu Siddique, MD, Les Turner ALS Foundation/Herbert C. Wenske Professor, Professor of Neurology and Cell and Molecular Biology, were two of 140 …
Over $1 Million Committed to the Les Turner ALS Center for 2019
Creating a world free of ALS is our North Star. And we’re kicking off 2019 with over $1 million to fund research and clinical care at the Les Turner ALS Center! We’re excited to fund five novel research endeavors from …
Dr. Ozdinler published in Acta Neuropathologica
Hande Ozdinler, PhD, one of the lead researchers at our Les Turner ALS Center at Northwestern Medicine, and her collaborators just published new findings in the journal Acta Neuropathologica. From Dr. Ozdinler, “We for the first time discovered the cellular defects …
